Polynucleotides

POLYNUCLEOTIDE TREATMENT

Polynucleotides are an advanced injectable treatment designed to improve skin quality by supporting the skin’s natural repair and regeneration processes. Unlike traditional dermal fillers, polynucleotides are not intended to add facial volume or change the shape of your features. Instead, they work gradually to improve the condition, strength and appearance of the skin.

Polynucleotides are purified chains of nucleotides—the building blocks of DNA—usually obtained from highly purified fish-derived sources. When carefully injected into the skin, they create a supportive environment for fibroblasts, the cells involved in the production of collagen, elastin and other components of the extracellular matrix.

The treatment may help improve hydration, elasticity, firmness and overall skin texture while softening the appearance of fine lines. Polynucleotides are especially useful in delicate areas, including the skin around the eyes, where heavier injectable products may not always be appropriate.

At Injector Maya, every polynucleotide treatment begins with a detailed medical consultation and skin assessment. The product, injection technique and treatment programme are selected according to the condition of your skin, the area being treated and your individual goals.

Results develop gradually as the skin’s regenerative processes are supported. The aim is healthier-looking, smoother and more resilient skin while maintaining a completely natural appearance.

WHAT CAN POLYNUCLEOTIDE IMPROVE?

Polynucleotide treatment may be recommended for:

Fine lines and early signs of ageing
Crepey or thinning skin
Tired-looking skin
Reduced firmness and elasticity
Dehydrated or dull skin
Fine lines around the eyes
Dark or tired-looking under-eye areas
Poor skin texture
Sun-damaged skin
Neck and décolletage rejuvenation
Skin preparation before other aesthetic treatments
Support for skin recovery following selected procedures

Results vary between patients, and a consultation is required to determine whether polynucleotides are appropriate for your concerns.

FREQUENTLY ASKED QUESTIONS

How Do Polynucleotides Work?

Polynucleotides are injected into the superficial layers of the skin using a series of small injections. They are believed to support fibroblast activity, hydration and tissue repair while helping to create a healthier environment within the skin.

Over time, this may improve elasticity, firmness, texture and the appearance of fine lines. Because this is a regenerative treatment, results appear progressively rather than immediately.

Which Areas Can Be Treated?

Polynucleotides can be used to treat several areas, including:

Under the eyes
Upper and lower eyelids, where clinically appropriate
Full face
Cheeks
Around the mouth
Neck
Décolletage
Backs of the hands
Selected areas of the body
Scalp, when using an appropriate product and treatment protocol

The product and injection technique must be chosen specifically for the area being treated.

What Are the Benefits of Polynucleotide Treatment?

Potential benefits include:

Improved skin hydration
Smoother skin texture
Increased firmness and elasticity
Reduction in the appearance of fine lines
Improved appearance of crepey skin
Fresher and more rested-looking skin
Natural-looking and gradual rejuvenation
Treatment of delicate areas such as the under-eyes
No artificial change to facial shape or expression
Minimal interruption to everyday activities for most patients

Are Polynucleotides the Same as Dermal Fillers?

No. Dermal fillers are primarily used to restore volume, enhance facial contours or support specific facial structures.

Polynucleotides are skin-regenerating injectables intended to improve skin quality. They do not create the same immediate lifting, contouring or volumising effect as traditional dermal fillers.

Depending on your concerns, polynucleotides may be used alone or as part of a personalised treatment plan alongside other procedures.

Are Polynucleotides the Same as Skin Boosters?

Although both treatments can improve skin quality, they work differently. Traditional skin boosters usually contain hyaluronic acid and focus predominantly on hydration.

Polynucleotides are used to support tissue repair and regenerative activity within the skin. Some treatment plans may include both approaches, depending on the patient’s needs.

How Many Treatments Will I Need?

Most patients are advised to complete an initial course of two to three treatments, usually performed two to four weeks apart.

The exact programme depends on:

The product being used
The area being treated
Skin condition and age
The concern being addressed
Individual response to treatment

A maintenance treatment may then be recommended approximately every four to six months. Your personal treatment plan will be discussed during your consultation.

When Will I See Results?

Some patients notice improved hydration and freshness within the first few weeks. Improvements in texture, firmness and elasticity usually develop gradually during the following weeks as the skin responds to treatment.

Results are not immediate and cannot be guaranteed. The most noticeable improvement is generally seen after completing the recommended treatment course.

How Long Do the Results Last?

The duration of results varies between patients and depends on age, skin condition, lifestyle, sun exposure, general health and the treatment protocol used.

Maintenance treatments are commonly recommended every four to six months to support the results.

Is the Treatment Painful?

Polynucleotides are administered using a very fine needle or cannula. You may feel a small scratch, pressure or temporary stinging during the injections.

A topical anaesthetic may be offered when appropriate to make the procedure more comfortable. Sensitivity varies depending on the treatment area and the individual patient.

Is There Any Downtime?

Polynucleotide treatment involves minimal downtime for most patients. Small raised bumps may be visible at the injection points immediately after treatment. These normally settle within several hours but can occasionally remain for longer, particularly around the eyes.

Temporary redness, swelling, tenderness or bruising may also occur. Periocular swelling can be more noticeable the following morning and may take several days to resolve.

It is advisable not to arrange treatment immediately before an important social or professional event.

What Side Effects Can Occur?

Expected and usually temporary effects include:

Redness
Swelling
Tenderness
Small injection-site bumps
Bruising
Mild itching
Minor bleeding at the injection points
Temporary unevenness while the product settles

Less common complications can include infection, prolonged swelling, inflammation, persistent lumps, skin discolouration, delayed reactions or an allergic response. Serious complications are uncommon, but no injectable treatment is entirely without risk.

You will receive detailed aftercare instructions and information about when to contact the clinic urgently.

Who Should Not Have Polynucleotide Treatment?

Treatment may not be suitable for people who:

Are pregnant or breastfeeding
Have an active infection, cold sore or inflammatory skin condition in the treatment area
Have a known allergy or hypersensitivity to fish, salmon, trout or any ingredient in the selected product
Have previously experienced a serious reaction to an injectable treatment
Have certain autoimmune, immune-system or uncontrolled medical conditions
Have an uncontrolled bleeding disorder
Are taking anticoagulants or medicines that significantly affect healing
Are currently undergoing certain cancer treatments or immunosuppressive therapy
Have recently undergone another procedure in the same area

Some conditions require individual assessment rather than automatic exclusion. A complete and accurate medical history must be provided during the consultation.

What Should I Avoid After Treatment?

Following your treatment, you will normally be advised to:

Avoid touching, rubbing or massaging the treated area unless instructed
Avoid applying make-up for at least 12 hours
Avoid strenuous exercise for 24–48 hours
Avoid alcohol for approximately 24 hours
Avoid saunas, steam rooms, hot baths and excessive heat for 48 hours
Avoid swimming for at least 48 hours
Avoid facials, massage and other treatments in the area until it has healed
Avoid strong acids, retinoids and irritating skincare products for several days
Protect the skin from direct sunlight and use a broad-spectrum SPF

Do not stop prescribed medication unless advised by the clinician responsible for your care.

Can Polynucleotides Be Combined With Other Treatments?

Yes. Polynucleotides may form part of a wider skin rejuvenation programme alongside treatments such as:

Treatments may need to be separated by an appropriate interval. Injector Maya will create a safe, personalised plan based on your skin, medical history and desired outcome.

Why Choose Injector Maya?

At Injector Maya, treatments are performed following a thorough consultation and medical assessment. We focus on safe patient selection, evidence-informed practice and natural-looking results.

Your treatment will be individually planned, with clear information about expected outcomes, possible side effects, aftercare and alternative options—including the option not to proceed.

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your concerns.*

NEED HELP IN CHOOSING THE RIGHT TREATMENT?

We’re here to help you achieve natural-looking results whatever your concerns.*

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